Mr. Ade Tunde has been plagued with hypertension. Several visits to the hospital have not yielded a desirable result, according to him, since all the doctors could do was manage his hypertension. After narrating his experience to his next-door-neighbour, he was given some garlic to chew, with the assurance that they would help cure his disease. Mr. Tunde later said that there was a marked improvement in his health, vowing that his doctors could testify to the fact.
Dr Olutayo Aderounmu, a practitioner with
Life Hospital, Ibadan, Oyo State, said despite
the health benefits of garlic, it could only
lower the risk of hypertension in people
and not cure it, saying that hypertension in
itself, could not be cured, but managed.
Garlic's abilities to curb many health
ailments and to naturally lower blood
pressure, including pulmonary
hypertension, have been documented for
over 5,000 years; thus making it one of the
most effective herbs to lower blood
pressure and increase your overall heart
health, Jon Butts wrote in his article on
Garlic and Hypertension.
He added that “even without first-hand
scientific proof, people throughout the ages
have been benefiting from these marvelous
cloves of the earth.”
Folks in some rural parts of Nigeria such as
Igangan, Ibarapa, Oyo State; Ibeto, Magama
Local Government of Niger State, and some
other eastern parts, have over the years,
employed the healing particles in garlic to
fight infections and, as a preservative. In
the ancient Egypt, garlic is used to increase
a soldier’s strength in battle. They also have
been known to bury their royalty with it.
References to garlic’s healing property have
also been found in Egyptian, Greek, Roman,
Chinese, and Indian medical texts.
As such, “it should be no surprise that the
power of garlic has finally been proven to
lower high blood pressure and the
propensity for other cardiovascular
diseases,” Butts concluded.
A study has found that garlic may be useful
in treating high blood pressure. In the study
conducted by Australian doctors, 50
patients were enrolled in a trial to see if
garlic supplements could help those whose
blood pressure was high, despite
medication.
The result of the study, reported in the
Scientific Journal Maturitas, suggested that
respondents who were given four capsules
of garlic extract a day had lower blood
pressure than those on placebo.
In a latest study conducted by researchers
from the University of Adelaide, Australia,
garlic was found to be good for the heart.
The head of the research, Karin Ried, while
reporting on the result of the study, said,
"Garlic supplements have been associated
with a blood pressure lowering effect of
clinical significance in patients with
untreated hypertension.
"Our trial, however, is the first to assess the
effect, tolerability and acceptability of aged
garlic extract as an additional treatment to
existing antihypertensive medication in
patients with treated, but uncontrolled,
hypertension."
In the study, the researchers looked at the
effects of four capsules a day of a
supplement known as aged garlic for 12
weeks. Their findings indicated systolic
blood pressure was around 10mmHg lower
in the group given garlic compared with
those given a placebo.
Garlic supplements have previously been
shown to lower cholesterol and reduce high
blood pressure in those with untreated
hypertension.
A senior cardiac nurse at the British Heart
Foundation, Ms Ellen Mason, while speaking
on the effects of garlic on hypertension
patients, said the use of garlic for medicinal
purposes dates back to thousands of years.
According to her, it is essential that scientific
research proves that garlic can help
conditions such as raised blood pressure.
"This study demonstrated a slight blood
pressure reduction after using aged garlic
supplements but it's not significant enough
or in a large enough group of people to
currently recommend it instead of
medication.
"It's a concern that so many people in the
United Kingdom have poorly controlled
blood pressure, with an increased risk of
stroke and heart disease as a consequence.
So enjoy garlic as part of your diet but don't
stop taking your blood pressure
medication."
Additionally, a study conducted at the
University of Alabama at Birmingham (UAB),
attributed garlic's ability to lower high
blood pressure to hydrogen sulfide content.
In a report by Foushee DD, Ruffin J and
Banerjee U, Garlic As a Natural Agent for the
Treatment of Hypertension: A Preliminary
Report, the major objective of the study
was to re-evaluate the effects of garlic on
blood pressure with respect to its ability to
provoke a decrease in blood pressure and
to determine the length of time that this
decrease would require.
They wrote that some hypertensive rats
were given three doses of garlic extract of
0.1 ml/kg, 0.25 ml/kg, and 0.5 ml/kg by oral
injection. The blood pressures of these
ether-anaesthetised rats were measured
immediately before the extract was given,
and then 0.5, 2, 4, 6, and 24 hours after the
extract were given. A blood pressure
measurement was also taken at 48 hours
after extract administration for the 0.5 ml/
kg dose.
Consequently, “there was a marked
decrease in the systolic blood pressure of all
of the rats after three doses and the
decrease occurred within 30 min in each
case.
“Even though the average decreases for the
0.1 ml/kg and the 0.25 ml/kg doses were
calculated as 51,25 mm Hg and 56.25 mm
Hg, respectively, these doses were not
sufficient to sustain the blood pressure in a
normal range for more than one or two
hours The 0.5 ml/kg dose, showing an
average decrease of 65.7 mm Hg, was
sufficient to provoke a decrease to a normal
level and to sustain this decrease for up to
24 hours.
“The results indicate that garlic is effective
as a natural agent for the treatment of
hypertension.”
Professor Helen Ekaete, a researcher,
explained that allicin, a compound found in
garlic is beneficial to the arterial health. She
said that allicin (a polysulfide) is the primary
biological compound found in garlic and is
widely accepted as the standard substance
responsible for garlic's ability to lower high
blood pressure and curb subsequent
cardiovascular problems.
“In short,” Butts wrote, “allin is the garlic
plant's primary immune system; thus
keeping it safe from the myriad of soil
microbes eager to feast on the tasty bulbs.
“Although toxic in large amounts, hydrogen
sulphide is naturally produced by the body
to serve a very beneficial purpose: to
control blood pressure naturally. In a sort of
paradoxical way, the same gas that offers
the pungent smell of rotting eggs and
odiferous sewers is now attributed to
reducing hypertension. This is amazing
science.
“Once released, the hydrogen sulphide
targets unique cell-membrane channels to
begin smooth muscle relaxation up to 72
per cent in laboratory animals. Such results,
therefore, classify hydrogen sulphide as a
local signaling gas: e g. a gas acting as a
catalyst within a cell.”
Professor Ekaete, who warned that even
though there were documented
cardiovascular benefits of allicin and
hydrogen sulphide, said it was important to
understand the limits to their benefits, said
to enjoy allicin in garlic, it should be
crushed, not sliced, among others.
Please indicate in your comments for the products and other information.
Wednesday, April 30, 2014
Bitter Leaf, Pumpkin Leaf Provide Solutions To Heart Attack.
Bitter leaf, ugu: Vegetables that can ward off heart problem Heart attack can lead to heart failure, a term that refers to an obstruction to the
blood supply to the heart. Aside the heart pumping blood to the body, it supplies itself
with blood. When it does not supply itself
with blood or the supply becomes obstructed, heart attack happens. The typical blood flows to it is because it is a living tissue apart from the blood flowing through it. However, it is this obstruction in the blood flow to the heart muscles itself that leads to heart attack and it starts gradually. The
blood vessels starts to be choked up, causing what is called arthelocolsosis and over time the problem becomes complicated because the affected blood vessel, the artery, also becomes dead. This is what
causes heart attack.
But before heart attack comes, gradually
from the age of 20, the inner layer of blood
vessels starts developing fat deposit in
them. The fats are deposited in them for
several reasons including hypertension,
high cholesterol in the blood, diabetes,
smoking, sedentary lifestyle, family history
and wrong diets.
Given that the heart is a pump it must
function properly to meet the need of the
body. If there is a problem within the heart
or around it preventing it from pumping
blood to other parts of the body, heart
failure may occur. Meanwhile, many things
can affect this “pump” and make it fail. Just
as heart attack can lead to heart failure, a
common cause of heart failure is
hypertension.
Hypertension is the commonest cause of
heart failure in Nigeria and, to some extent
an individual can guess his chances of
developing heart disease because it is an
interplay of cholesterol, hypertension, and
diabetes. In fact, the World Health
Organisation (WHO) estimates that almost
20 per cent of all strokes and over 50 per
cent of all heart attacks can be linked to
high cholesterol.
Cholesterol is a fat-like substance circulating
in the blood. Some of this cholesterol comes
from the foods consumed. But the bulk of it
is actually made in the body, specifically in
the liver, because the body needs it to make
some hormones and support the function
of body cells. But an excess of it in the
bloodstream can lead to trouble.
Cholesterol comes in several different
forms, but doctors focus mostly on two: LDL
cholesterol and HDL cholesterol. LDL is also
called “bad cholesterol” and it is termed bad
because if its level is too high, the excess
can accumulate on the walls of the arteries.
This build-up of cholesterol and other
substances called plaque, can narrow the
artery like a clogged drain, leading to
arteriosclerosis, or hardening of the
arteries. This makes the normally flexible
tissue more brittle. Plaques can form
anywhere. If they form in the carotid artery
in the neck, what results is carotid artery
disease.
When they form in the coronary arteries —
which supply the heart muscle with blood
— it’s called coronary artery disease. Like
any organ, the heart needs a good supply
of blood to work. If it doesn’t get that blood,
one could get angina, which causes a
squeezing pain in the chest, among other
symptoms.
Notwithstanding, regular consumption of
vegetables such as Vernonia amygdalina
(bitter leaf )and Telfairia occidentalis (Ugu)
can help to regulate the blood’s cholesterol
level. Wondering why? In a study on
comparative effects of the leaves of bitter
leaf and Ugu incorporated diets on the
lipid profile of rats, it was apparent that the
two diet preparations lowered the blood
(serum) cholesterol levels though the Ugu
diet induced a higher effect at lower
concentrations.
The 2011 study published in the African
Journal of Biochemistry Research involved
C. E. Ugwu and J. E. Olajide from the
Department of Biochemistry, Kogi State
University, Anyigba, in collaboration with E.
O. Alumana and L. U. S. Ezeanyika from the
Department of Biochemistry, University of
Nigeria, Nsukka, Enugu State. It was entitled:
“Comparative effects of the leaves of
Vernonia amygdalina and Telfairia
occidentalis incorporated diets on the lipid
profile of rats”.
The treatment of hypertension has failed to
show definitive effect on the incidence of
coronary heart disease, which has aroused
interest in lipid metabolism in hypertensive
therapy.
The results from the study showed that the
treatment with bitter leaf and ugwu diets
led to a significant increase in serum HDL-C,
showing their protective role in
cardiovascular diseases (CVD). The
comparison of their effects showed that
ugwu diet preparation stimulated a
considerable increase in serum HDL-C
compared to bitter leaf.
Vernonia amygdalina, also called bitter leaf
because of its bitter taste, is a shrub that
grows predominantly in Tropical Africa. The
leaves have found relevance in traditional
folk medicine as a dewormer, a laxative
herb and an antimalarial as they are known
as quinine substitute. They are also used in
the treatment of cough and hypertension.
Telfairia occidentalis (fluted pumpkin or
Ugwu) leaves and young shoots are
frequently eaten as a potherb. The herbal
preparation of the plant has been employed
in the treatment of sudden attack of
convulsion, malaria and anaemia.
The seed of fluted pumpkin is widely
consumed in Nigeria, especially in the
southeastern part of Nigeria where it is
used as a condiment in soup. The fermented
seeds of fluted pumpkin are used in the
production of “Ogiri ugu”, a locally made
custard. The seeds of fluted pumpkin could
also be used in cookie formulations and
marmalade manufacturing. The seed is also
a good source of edible oil.
They wrote: “the results from this study
confirm that V. amygdalina and T.
occidentalis have lipid lowering effects
which may be beneficial to people at risk of
CVD. V. amygdalina and T. occidentalis were
found to be effective in lowering the levels
of serum cholesterol, triacylglycerols and
LDL-C, thereby, showing their
hypocholesterolaemic(reducing cholesterol
level) property. These leaves could be
beneficial to people at high risk of
cardiovascular disease.”
In carrying out the study, the rats were fed
for 28 days on diets specially formulated to
contain 5, 15 and 30 per cent by weight
respectively of the leaves of each plant
while the control group was fed standard
rat diet. The serum total cholesterol (TC),
triacylglycerol (TG), high-density lipoprotein
cholesterol (HDL-C) and low-density
lipoprotein cholesterol (LDL-C) were
determined on blood samples collected on
the 28th day using standard methods.
Certainly, different foods lower cholesterol
in various ways but another easy step to
ensure a safe cholesterol level is having a
bowl of oatmeal for breakfast. Beans,
eggplant and okra are especially rich in
soluble fibre that mops up cholesterol.
Substituting your cooking oil with
vegetable oils, such as canola and
sunflower, helps to lower LDL. Fruits such as
apples, grapes, strawberries and citrus
fruits are rich in pectin, a type of soluble
fibre that lowers LDL.
In addition, eating fishes two or three times
a week can lower LDL by replacing meat,
which has LDL-boosting saturated fats, and
by delivering LDL-lowering omega-3 fats.
Omega-3s reduce triglycerides in the blood
stream and also protect the heart by helping
to prevent the onset of abnormal heart
rhythms.
Interestingly, researchers stated in the
Pakistan Journal of Nutrition that garden
egg was the best when a comparison study
was carried on on apple, oat and garden
egg. They pointed out that “garden egg
significantly reduced the total cholesterol
and triglyceride as well as increased the HDL
compared to oat and apple in both the mid-
term and full-term studies.” Contact us through your comment for more on these products.
Tuesday, April 29, 2014
BITTER KOLA EFFECTIVE FOR VOMITING, NAUSEA CONTROL.
Do you suffer every morning from pregnancy related nausea and vomiting? Maybe you easily get nauseated as a result of motion sickness or drug toxicity. Well, scientists
have reasons to recommend bitter kola as an antidote to nausea and vomiting. Scientists found that the ethanol extract of the seed of Garcinia kola(bitter kola) and its seed skin had ability to control vomiting and nausea, thus providing for the first time the rationale for its use in African traditional medicine in the management of nausea and vomiting. Garcinia kola, generally known as bitter kola is found in moist forest and grows as medium size tree, up to 12 m high. It is cultivated and distributed throughout west and central Africa. It has been referred to as a ‘wonder plant’ because almost every part of it has been found to be of medicinal importance. It is commonly called “Agbilu” in Igbo land and “Namijin goro” in Hausa and “orogbo” in Yoruba land of Nigeria. It produces a characteristic orange-like pod with seeds covered with a skin or husk.
All parts of the plant are used in traditional medicine for various therapeutic purposes. Extracts of the plant have been traditionally used for ailments such as laryngitis, liver diseases and cough. The seeds are used to prevent or relieve colic pains, cure head or chest colds, relieve cough and have anti-inflammatory, antimicrobial and antiviral properties. It is also used as an antidote for venomous stings and bites, and in the treatment of diarrhea and dysentery. It has been reported that the seeds is good for ulcer patients, the ethanol extract from the seeds to ameliorate pain and mild kidney insufficiency induced by the anticancer drug, cisplatin. Discomfort from drug induced emesis can deter a patient from taking further chemotherapeutic agent especially with the potentially curative anti cancer treatment Bitter kola was found helpful in ameliorating the pain and swelling experienced by people with knee osteoarthritis, good for prevention of ulcer and the cold water extract of root bark with salt is used in southern Nigeria against cough and vomiting. In southern Nigeria also, the seed is chewed to prevent nausea and vomiting in pregnancy and motion sickness. For the study, the researchers induced nausea and vomiting in chicks divided into six groups of five chicks each using copper sulphate. The chicks were then given different doses of the extracts of bitter kola to ascertain their effectiveness in controlling nausea and vomiting. These were compared with the effect of a positive control antiemetic drug (Metoclopromide 2mg/kg) and a negative control (normal saline) against copper sulphate induced emesis.
Researchers found that the seed extract at 50 and 150 mg/kg produced a percentage inhibition by 71.70 and 75.47 per cent respectively while the seed bark extract at 50 and 150 mg/kg produced a percentage inhibition by 47.16 and 62.27 per cent respectively. Also From the result, the seed extract protected the young chicks against emesis better than the seed skin extract. The 75 per cent inhibition produced by the seed extract especially the maximum dose of 150mg/kg administered was closer to the 81 per cent inhibition produced by metoclopramide. The researchers attributed the effectiveness of bitter kola seeds and seed skin extracts in reducing nausea and vomiting to its saponins, alkaloids or flavonoid contents. The study, which was published in 2010 edition of The Internet Journal of Alternative Medicine, was entitled “Preliminary Study of the Antiemetic Effect of Garcinia Kola Seed Extract in Young Chicks”. It was carried out by C.I Nosiri and Alewu B from the Faculty of Pharmaceutical Sciences, Ahmadu Bello University, Zaria in collaboration with Gambo Abba from the School of Public Health Nursing, Shehu Idris College of Health Sciences and Technology, Makarfi.
Vomiting is one of the most commonly experienced natural reflexes. Although we may not vomit often, or on a regular basis, we have all vomited at some point of time. Vomiting in itself is not a health condition, but it is a body response or reaction to certain conditions, or a symptom of some disease or disorder. Ginger is an herb that has been a member of some medical cultures for centuries treat a variety of problems. The University of Maryland Medical Center reported that the benefits of ginger may include arthritis relief, a treatment for the common cold and assistance for those with menstrual cramps. A 2009 study from the National Cancer Institute found that taking a dietary supplement with ginger could help relieve nausea in patients undergoing
chemotherapy. If nausea and vomiting are persistent, other home remedies that can be used include lemon juice. Mix together 1 teaspoon honey and 1 teaspoon lemon juice. Dip your finger into the mix and lick it off so that you take it in slowly. In addition, lime juice might be helpful as an immediate nausea/vomiting stopper. Mix a cup water with 10 drops lime juice and 1/2 teaspoon sugar. Then add 1/4 teaspoon baking soda and drink. Peppermint can also help to ease cramping and settle the stomach. It is also reputed for quelling nausea. It is a good choice of herb for nausea accompanied by a headache, or a cold since is a good remedy for both ailments.
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